• br The role of P

  2019-05-09

  

  The role of P62 in tumors The role of P62 in osteoclastogenesis P62 as an oncotarget for treatment Concluding remarks P62 is a cellular “Swiss army knife,” with its diverse cellular functions arising from its unique functional motifs and protein–protein interaction properties. P62 may pl

• Education and lifestyle changes for the prevention of

  2019-05-09

  

  Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev

• br Alternans and arrhythmogenesis in different clinical cond

  2019-05-09

  

  Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a

• The appearance of J wave

  2019-05-09

  

  The appearance of J wave or ER is now recognized to predispose to the development of arrhythmogenesis when associated with other cardiac disorders, such as ischemia, UNC1999 cost failure, and hypothermia. The J wave might predict prognosis of cardiac events in various heart diseases, and the appear

• Era tal el recelo que hab a sobre el

  2019-05-09

  

  Era tal el recelo que había sobre el enriquecimiento de los ministros que en enero de 1622 se intentó investigar los orígenes de su riqueza. El mismo mes se publicó un decreto que estipulaba que todos los que habían tenido cargos supplier partir de 1592 debían inventariar sus propiedades ante un jue

• Pregnancies in adolescents year olds and in older women

  2019-05-09

  

  Pregnancies in adolescents (10–19-year-olds) and in older women (≥35 years) are hazardous for the mother and the child. Despite an almost universal decline in the adolescent 4-ap since 1990, adolescent fertility still accounts for 11% of all births worldwide, with 95% of these births occurring in l

• br El nacionalismo entendido como una ideolog

  2019-05-09

  

  El nacionalismo, entendido como una ideología y un movimiento político-social, aparece con el concepto moderno de la nación como respuesta TAPI-1 una necesidad urgente de legitimar el nuevo orden político-social republicano, en el que la “soberanía del pueblo” reemplazaba al “derecho divino” de lo

• En conclusi n vivir bien buen vivir no son

  2019-05-09

  

  En conclusión, vivir bien/buen vivir no son por el momento nuevos paradigmas, pese a que, por ejemplo, los autores del Plan Nacional para el Buen Vivir de Ecuador (2009-2013) se referan a una transición del concepto de desarrollo al buen vivir en los términos de un “cambio de para-digma”. En estos t

• Por otro lado el proceso de negociaciones que

  2019-05-09

  

  Por otro lado, el proceso de negociaciones que llevan Myoseverin cabo ambos gobiernos, demuestra, según estudiosos estadounidenses, que hay un reconocimiento de parte de los funcionarios de Estados Unidos, de que Cuba está ayudando a poner fin a la insurgencia de las farc en Colombia, que pueden ten

• br Methods br Results br Discussion ICC

  2019-05-09

  

  Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi

• In the APHRS survey most respondents answered

  2019-05-09

  

  In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate

• br Hybrid approach It is still not

  2019-05-09

  

  Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc

• br Conflict of interest statement

  2019-05-09

  

  Conflict of interest statement Acknowledgments The authors would like to thank Dr. Bjørn Naume, and Dr. Erik Løkkevik from the Department of Clinical Oncology, the Norwegian Radium Hospital for their helpful comments. This study was supported by grants from the Norwegian Radium Hospital Founda

• br We recently reported associations between

  2019-05-08

  

  We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( Antimicrobial resistance is recognised as a serious global he

• La Constituci n espa ola de dispone bajo el

  2019-05-08

  

  La Constitución española de 1812 dispone bajo el nombre de América septentrional un territorio que desde California, Nuevo México y Texas hasta la Capitanía de Guatemala conforma una inmensa, compleja y rica estructura administrativa. Guatemala se separa poco antes de la jura de la Constitución de 1

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